Richard Mohs Selected Research

N2- ((2S)- 2- (3,5- difluorophenyl)- 2- hydroxyethanoyl)- N1- ((7S)- 5- methyl- 6- oxo- 6,7- dihydro- 5H- dibenzo(b,d)azepin- 7- yl)- L- alaninamide

1/2015	Peripheral and central effects of γ-secretase inhibition by semagacestat in Alzheimer's disease.
1/2015	Cognitive Impairment Precedes and Predicts Functional Impairment in Mild Alzheimer's Disease.
7/2013	A phase 3 trial of semagacestat for treatment of Alzheimer's disease.

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Richard Mohs Research Topics

Disease

9	Alzheimer Disease (Alzheimer's Disease) 01/2018 - 03/2003
3	Cognitive Dysfunction 01/2015 - 07/2013
2	Dementia (Dementias) 04/2004 - 03/2003
1	Vomiting 01/2016
1	Major Depressive Disorder (Major Depressive Disorders) 01/2016
1	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2016
1	Mood Disorders (Mood Disorder) 01/2016
1	Alcoholism (Alcohol Abuse) 01/2016
1	Hemorrhage 01/2014
1	Edema (Dropsy) 01/2014
1	Gliosis 01/2014
1	Infections 07/2013
1	Skin Neoplasms (Skin Cancer) 07/2013
1	Fibromyalgia (Fibrositis) 07/2012
1	Psychotic Disorders (Schizoaffective Disorder) 04/2004
1	Disease Progression 03/2003
1	Amyloid Plaque 03/2003

Drug/Important Bio-Agent (IBA)

4	solanezumabIBA 01/2018 - 07/2012
3	N2- ((2S)- 2- (3,5- difluorophenyl)- 2- hydroxyethanoyl)- N1- ((7S)- 5- methyl- 6- oxo- 6,7- dihydro- 5H- dibenzo(b,d)azepin- 7- yl)- L- alaninamideIBA 01/2015 - 07/2013
3	Amyloid (Amyloid Fibrils)IBA 01/2014 - 07/2012
2	LY2940094IBA 01/2016 - 01/2016
2	NociceptinIBA 01/2016 - 01/2016
2	Biomarkers (Surrogate Marker)IBA 01/2015 - 07/2012
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2015 - 07/2013
2	Amyloid beta-PeptidesIBA 01/2014 - 07/2013
1	Pharmaceutical PreparationsIBA 01/2018
1	Antidepressive Agents (Antidepressants)IBA 01/2016
1	Nociceptin ReceptorIBA 01/2016
1	LigandsIBA 01/2016
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2016
1	Peptide Receptors (Peptide Receptor)IBA 01/2016
1	TransferasesIBA 01/2016
1	Proteins (Proteins, Gene)FDA Link 07/2013
1	Duloxetine Hydrochloride (Cymbalta)FDA Link 07/2012
1	Messenger RNA (mRNA)IBA 03/2003
1	CaspasesIBA 03/2003
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 03/2003

Therapy/Procedure

4	Activities of Daily Living (ADL) 01/2015 - 04/2004
1	Therapeutics 07/2009
1	Home Nursing (Nursing, Home) 03/2003